%0 Journal Article
%T Perfil lip赤dico en el suero de conejos tratados con etanol y dieta hipercolesterol谷mica
%A Aleida Herrera Batista
%A Isis Lebredo 芍lvarez
%A Ela C谷spedes Miranda
%A Leonel Falc車n Vila迆
%J Revista Cubana de Investigaciones Biomˋˋdicas
%D 2003
%I ECIMED
%X Se pretendi車 determinar las posibles variaciones del perfil lip赤dico del suero ante la ingesti車n de etanol y de una dieta hipercolesterol谷mica. Se utilizaron 22 conejos machos de 100 d de nacidos, se conformaron 4 grupos: tratados con alcohol, con dieta rica en colesterol, con alcohol y dieta rica en colesterol y un grupo control. El experimento dur車 16 semanas. Se les realiz車 lipidograma a todos los conejos y se analizaron las variables colesterol total, triacilglic谷ridos, lipoprote赤nas de alta densidad, lipoprote赤nas de baja densidad y lipoprote赤nas de muy baja densidad. Se comprob車 que la ingesti車n cr車nica de alcohol elev車 colesterol total, lipoprote赤nas de alta densidad, y disminuy車 triacilglic谷ridos y lipoprote赤nas de muy baja densidad. Los animales tratados con dieta rica en colesterol y los tratados con dieta y alcohol presentaron valores elevados de colesterol total, lipoprote赤nas de baja densidad, triacilglic谷ridos y lipoprote赤nas de muy baja densidad. Los resultados de la presente investigaci車n llevan a la conclusi車n que el alcohol no ofrece protecci車n antiaterog谷nica, al menos a las dosis utilizadas en este estudio. The purpose of this paper was to determine the possible variations of the lipid profile of serum brought about by the ingestion of ethanol and of a hypercholesterolemic diet. 22 male rabbits aged 100 days were used. They were divided into 4 groups: the first was treated with alcohol, the second with a high-cholesterol diet, the third with alcohol and a high-cholesterol diet and the fourth was a control group. The experiment lasted 16 weeks All the rabbits underwent lipidograms. The following variables were analyzed: total cholesterol, triacilglycerides, high density lipoproteins, low density lipoproteins, and very low density lipoproteins. It was proved that the chronic ingestion of alcohol increased total cholesterol and high density lipoproteins, and reduced triacilglycerides and very low density lipoproteins. Those animals treated with a high-cholesterol diet and with diet and alcohol showed elevated values of total cholesterol, low density lipoproteins, triacilglycerides and very low density lipoproteins. According to the results, it was concluded that alcohol does not offer antiatherogenic protection, at least at the doses used in this study.
%K ALCOHOLISMO
%K ADOLESCENTE
%K ATEROSCLEROSIS
%K LIPOPROTE赤NAS DEL COLESTEROL HDL
%K LIPOPROTE赤NAS DEL COLESTEROL LDL
%K CONEJOS
%K ALCOHOLISM
%K ADOLESCENT
%K ATHEROSCLEROSIS
%K LIPOPROTEINS
%K HDL CHOLESTEROL
%K LIPOPROTEINS
%K LDL CHOLESTEROL
%K RABBITS
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03002003000200008