%0 Journal Article %T Alteraciones morfom¨¦tricas de los hepatocitos de ratas albinas que ingieren alcohol desde la adolescencia %A Maritza Gonz¨¢lez Bravo %A Aleida Herrera Batista %A Rosa Mar¨ªa Coro Antich %A Giselle Puld¨°n Segui %J Revista Cubana de Investigaciones Biom£¿£¿dicas %D 2003 %I ECIMED %X Se estudi¨® el h¨ªgado, se midieron las variables: ¨¢rea n¨²cleo, ¨¢rea citoplasma, y relaci¨®n n¨²cleo citoplasma de los hepatocitos de las zonas periportal, intermedia y perivenosa. Se utilizaron 40 ratas de uno y otro sexos, conform¨¢ndose 2 grupos: alcoh¨®licas y controles. A las alcoh¨®licas se le suministr¨® etanol 40 % diluido en agua desde los 28 hasta los 90 d de nacidas, por v¨ªa oral y mediante una c¨¢nula intraesof¨¢gica. Las variables morfom¨¦tricas ¨¢rea n¨²cleo y la relaci¨®n n¨²cleo citoplasma resultaron estad¨ªsticamente diferentes y mayores en las ratas alcoh¨®licas. The liver was studied, and the following variables were measured: nucleus area, cytoplasm area, and nucleus cytoplasm relation of the hepatocytes of the periportal, intermediate and perivenous zone. 40 rats of both sexes were used to have 2 groups: alcoholics and controls. The alcoholic between 28 and 90 days old were administered ethanol 40 % diluted in water by oral route by an intraesophageal cannula. The morphometric variables such as nucleus area and the relation nucleus cytoplasm proved to be statistically different and higher among alcoholic rats. %K ALALCOHOLISMO %K HEPATOPAT¨ªAS %K ADOLESCENTE %K RATAS %K ALCOHOLISM %K LIVER DISEASES %K ADOLESCENT %K RATS %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03002003000200007