%0 Journal Article
%T Evaluaci車n farmacogn車stica y fitoqu赤mica preliminar de hyllanthus rbicularis HBK
%A Yamilet Irene Guti谷rrez Gait谷n
%A Migdalia Miranda Mart赤nez
%A Gloria del Barrio
%A Noel Varona Torres
%J Revista Cubana de Farmacia
%D 2000
%I ECIMED
%X Se realiz車 un estudio farmacogn車stico y fitoqu赤mico preliminar de Phyllanthus orbicularis HBK, donde se determinaron inicialmente las caracter赤sticas macromorfol車gicas y micromorfol車gicas de las hojas y tallos de la especie. Se estandariz車 la droga cruda, cuyos valores promedio obtenidos se encontraban dentro del rango permisible, cuando los comparamos con los de drogas oficiales. Se determin車 la composici車n qu赤mica general de la droga mediante ensayos de tamizaje fitoqu赤mico, y se detect車 la presencia de flavonoides, alcaloides, coumarinas, saponinas, amino芍cidos, antocianidinas, muc赤lagos, triterpenos y/o esteroides, sustancias reductoras, taninos pirocatec車licos, principios amargos y astringentes, glic車sidos y quinonas. Tambi谷n se cuantificaron algunos de estos metabolitos. Se procedi車 finalmente, a la extracci車n y fraccionamiento de flavonoides, obteni谷ndose fracciones muy simples con la presencia de dichos compuestos; adem芍s, se detecta rutina y quercetina, as赤 como 2 compuestos cromatogr芍ficamente puros, que seg迆n los an芍lisis efectuados se sospecha que sean flavonoides. We performed a preliminary pharmacognosic and phytochemical study of Phyllanthus orbicularis HBK where the macro- and micromorphologic features of stems and leaves of this plant were inicially determined. We standardized the raw drug whose average values were tithin the allowable range if compared to those of the official drugs. Through phytochemical sieving tests, we determined the general chemical composition of this drug in which the presence of flavonoids, alkaloids, coumarins, saponins, aminoacids, anthocyanidins, mucilages, triterpenes and or steroids, reducing substances, pyrocathecolic tannins, bitter and astringent principle, glycosides and quinones. Also some of these metabolites were quantified. Finally, we carried out the extraction and fractioning of flavonoids into very simple fractions having these compounds. Also rutine and quercentin were detected together with two chromatographically pure compounds which, according to the tests applied, are suspected to be flavonoids.
%K PLANTAS MEDICINALES
%K TALLOS DE PLANTAS
%K HOJAS DE PLANTAS
%K PLANTS
%K MEDICINAL
%K PLANT STEM
%K PLANT LEAVES
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75152000000100008