%0 Journal Article
%T Farmacovigilancia intensiva en pacientes adultos y pedi¨¢tricos
%A Isis B Berm¨²dez Camps
%A Nailet Real Bestard
%A Jos¨¦ R Acosta Torres
%A Aurelio Rodr¨ªguez Fern¨¢ndez
%J Revista Cubana de Farmacia
%D 1999
%I ECIMED
%X Se estudiaron 600 pacientes, 320 ni os y 280 adultos seleccionados aleatoriamente a partir de los 2 368 casos ingresados en las unidades de cuidados intensivos e intermedios de los hospitales Infantil Norte "Juan de la Cruz Mart¨ªnez Maceira" y Provincial Clinicoquir¨²rgico Docente "Saturnino Lora". Se detectaron 511 reacciones adversas a medicamentos en 261 pacientes, 187 adultos y 74 ni os, con un ¨ªndice de aparici¨®n de este fen¨®meno del 61 y 20 % respectivamente. Los resultados obtenidos fueron procesados y evaluados mediante pruebas estad¨ªsticas, la aplicaci¨®n del algoritmo de Naranjo y el c¨¢lculo del beneficio-riesgo de los tratamientos aplicados. 600 patients (320 children and 280 adults) were studied, who had been ramdonly selected from 2 368 cases admitted to the intensive and intermidiate care units in "Juan de la Cruz-Mart¨ªnez Maceira" Northern Pediatric Hospital and "Saturnino Lora" Provincial Teaching Clinicosurgical Hospital. 511 adverse reactions to drugs were detected in 201 patients 187 adults and 74 children- with an occurrence index of 61 % and 20 % respectively. The result were processed and asseased through statistical tests, Naranjo¡¯s algoritthm and benefit- risk analysis of used treatments.
%K SISTEMAS DE REGISTRO DE REACCION ADVERSA A MEDICAMENTOS
%K UNIDADES DE TERAPIA INTENSIVA
%K ADEVERSE DRUG REACTION REPORTING SYSTEMS
%K INTENSIVE CARE UNITS
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75151999000200005