%0 Journal Article
%T Alcaloides en la especie cubana Croton micradenus Urb
%A Armando Payo Hill
%A Daisy Sandoval L車pez
%A Herm芍n V谷lez Castro
%A Marledis Oquendo Su芍rez
%J Revista Cubana de Farmacia
%D 2001
%I ECIMED
%X Se emprendi車 el estudio del contenido de alcaloides en las hojas y tallos de la especie end谷mica cubana, potencialmente medicinal, Crot車n micradenus Urb. Para la extracci車n y purificaci車n de dichos metabolitos se utilizaron solventes org芍nicos y m谷todos cromatogr芍ficos de separaci車n por columna y placa. Mediante m谷todos espectrosc車picos de UV, IR, Masa y RMN 1H y 13C, as赤 como por la medici車n de sus constantes f赤sicas, se caracterizaron 4 de los 6 alcaloides aislados, de ellos 3 morfinandienonas: ocobotrina, sinoacutina y 8,14 dihidrosalutaridina y una aporfina: isoboldina. The study of the content of alkaloids in the leaves and stems of the Croton micradenus Urb Cuban endemic species, which is potentially medicinal, was conducted. Organic solvents and chromatographic methods of separation by column and plate were used for the extraction and purification of these metabolites. 4 of the 6 isolated alkaloids, 3 of them morphinandienones: ocobotrine, sinoacutine and 8,14-dihydrosalutaridine and an aporphine (Isobol-dine) were characterized by spectroscopic methods of UV, IR, Mass and NMR 1H and 13C, as well as by the measurement of their physical constants.
%K ALCALOIDES
%K PLANTAS MEDICINALES
%K EXTRACTOS VEGETALES
%K QUIMICA FARMACEUTICA
%K CROMATOGRAFIA EN CAPA DELGADA
%K ALCALOIDES
%K ESPECTROMETRIA DE MASA
%K ALKALOIDS
%K PLANTS
%K MEDICINAL
%K PLANT EXTRACTS
%K CHEMISTRY
%K PHARMACEUTICAL
%K CHROMATOGRAPHY
%K THIN LAYER
%K ALKALOIDS
%K SPECTRUM ANALYSIS
%K MASS
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75152001000100011