%0 Journal Article
%T Behavioral mechanisms and morphological symptoms of zombie ants dying from fungal infection
%A David P Hughes
%A Sandra B Andersen
%A Nigel L Hywel-Jones
%A Winanda Himaman
%A Johan Billen
%A Jacobus J Boomsma
%J BMC Ecology
%D 2011
%I BioMed Central
%R 10.1186/1472-6785-11-13
%X We found that infected ants behave as zombies and display predictable stereotypical behaviors of random rather than directional walking, and of repeated convulsions that make them fall down and thus precludes returning to the canopy. Transitions from erratic wandering to death grips on a leaf vein were abrupt and synchronized around solar noon. We show that the mandibles of ants penetrate deeply into vein tissue and that this is accompanied by extensive atrophy of the mandibular muscles. This lock-jaw means the ant will remain attached to the leaf after death. We further present histological data to show that a high density of single celled stages of the parasite within the head capsule of dying ants are likely to be responsible for this muscular atrophy.Extended phenotypes in ants induced by fungal infections are a complex example of behavioral manipulation requiring coordinated changes of host behavior and morphology. Future work should address the genetic basis of such extended phenotypes.Some parasites can adaptively take over and completely control the behavior of their hosts leading to positive fitness returns for parasite genes [1-4]. Host behavior is an extended phenotype of the parasite [5]. The degree of behavioral manipulation varies greatly across parasites from very slight alterations of pre-existing behaviors [6] to the expression of wholly novel behaviors that are never seen in healthy hosts [7]. Extended phenotypes have gained considerable prominence in community- [8], evolutionary- [9] and behavioral ecology [10].Early studies of extended phenotypes focused on detailing behavioral changes and inferring whether they represent adaptations for parasites or should rather be interpreted as adaptive defense mechanisms of the host or as by-products of infection [11-13]. Recently, more integrative approaches have emerged which includes a greater focus on the mechanisms by which behavioral changes occur. An important component is a fuller understanding of th
%K extended phenotype
%K behavioral manipulation
%K ants
%K fungi
%K convergent evolution
%K parasites
%U http://www.biomedcentral.com/1472-6785/11/13