%0 Journal Article %T Metabolitos secundarios y actividad antimicrobiana de Pluchea carolinensis Secondary metabolites and antimicrobial activity of Pluchea carolinensis %A Wilmer Hervet Perera C車rdova %A Leonora Gonz芍lez Mesa %A Armando Luis Payo Hill %J Revista Cubana de Farmacia %D 2006 %I ECIMED %X Se le realiz車 un tamizaje fitoqu赤mico a las hojas de la especie Pluchea carolinensis Jacq. G. Don in Sweet y se sometieron a un fraccionamiento con el empleo de solventes de polaridad creciente. En cada uno de los extractos obtenidos se verific車 la presencia de flavonoides y se evalu車 la actividad antimicrobiana frente a 7 microorganismos. Se detect車 la presencia de flavonoides en los extractos CHCl3, AcOEt y n-BuOH, los que presentaron actividad antibacteriana. El extracto CHCl3 present車 actividad biol車gica frente a Bacillus subtilis a una concentraci車n de 1 000 米g/mL, mientras que los extractos AcOEt y n-BuOH mostraron resultados positivos frente a las bacterias Staphylococcus aureus y Bacillus subtilis a la misma concentraci車n A phytochemical screening was carried out in the leaves of the species Pluchea carolinensis Jacq. G. Don in Sweet, and they were subjected to fractioning by using increasing polarity solvents. The presence of flavonoids was confirmed in each of the extracts obtained, and the antimicrobial activity against 7 microorganisms was evaluated. The presence of flavonoids was detected in CHCl3, AcOEt and n-BuOH extracts, which presented antibacterial activity. The CHCl3 extract showed biological activity against Bacillus subtilis at a concentration of 1 000 米g/mL, whereas the AcOEt and n-BuOH extracts had positive results against Staphylococcus aureus y Bacillus subtilis bacteria at the same concentration %K Tamizaje fitoqu赤mico %K favonoides %K actividad antimicrobiana %K Pluchea carolinensis %K Asteraceae %K Phytochemical screening %K flavonoids %K antimicrobial activity %K Pluchea carolinensis %K Asteraceae %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75152006000200007