%0 Journal Article %T Nuevo indicador para el an¨¢lisis de las reacciones adversas a medicamentos que se prescriben por certificado m¨¦dico en Cuba New indicator for the analysis of adverse drug reactions that are prescribed in medical certificates in Cuba %A Mario Hern¨¢ndez Cueto %A Giset Jim¨¦nez L¨®pez %A Jenny ¨¢vila P¨¦rez %J Revista Cubana de Farmacia %D 2006 %I ECIMED %X Las sospechas de reacciones adversas medicamentosas constituyen un serio problema de salud en el mundo, y Cuba no est¨¢ excluida de ello. Mediante el Programa Nacional de Medicamentos implantado en el pa¨ªs al comienzo del decenio de los 90 se instituy¨® que un n¨²mero de medicamentos esenciales -78 incluyendo 3 productos que no lo son- en el tratamiento de las principales enfermedades cr¨®nicas no transmisibles, se prescribiesen mediante certificado m¨¦dico -desde entonces se conocen como medicamentos controlados- por lo que se obtuvo como beneficio secundario un registro continuo y permanente -entre otros aspectos- por producto y territorio, conoci¨¦ndose entonces la cantidad exacta de pacientes con esa prescripci¨®n. Basado en la fiabilidad y fortaleza de esa posibilidad, ¨²nica en Cuba por sus caracter¨ªsticas particulares, se construy¨® entonces un indicador que tomaba como poblaci¨®n expuesta, el registro que exhib¨ªa ese f¨¢rmaco en el nivel de atenci¨®n y tiempo que se deseaba estudiar. Comparado con el indicador cl¨¢sico, este mostr¨® m¨¢s verosimilitud al realizar la comprobaci¨®n con un grupo de medicamentos hipotensores y diur¨¦ticos a escala nacional durante el a o 2003. Se discuten sus resultados y se concluye que este indicador es superior a los usados hasta el momento para estos f¨¢rmacos Suspected adverse drug reactions are a serious health problem worldwide, and Cuba is not an exception. By means of the National Drug Program implemented in the country at the beginning of the 90¡äs, it was instructed that a number of essential drugs - a total of 78 including some non-fundamental products - for the treatment of the main non-conveyable chronic diseases should be prescribed using a medical certificate. Since then, these drugs were called controlled drugs, and a secondary benefit of this measure was a permanent record of products and territories where they are used, in addition to the exact number of patients with that prescription. On the basis of the reliability and strength of this record, which is unique in Cuba due to its particular characteristics, a new indicator was devised that took as the exposed population the record of a given drug at a level of care and the length of time that was intended to be studied. In comparison with the classical indicator, the new one was more credible in the verification of a group of antihypertensive and diuretic drugs at national level during 2003. The results achieved were discussed in this paper and it was concluded that this indicator is better than those so far used for these drugs %K Idincador %K reacciones adversas medicamentosas %K medicamentos controlados %K Programa Nacional de Medicamentos %K Cuba %K Indicator %K adverse drug reactions %K controlled drugs %K National Drug Program %K Cuba %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75152006000100003