%0 Journal Article %T Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning %A Behnam Sadeghi %A Suleiman Al-Hashmi %A Zuzana Hassan %A Bjorn Rozell %A Hernan Concha %A Carin Lundmark %A Kjell-Olov Gr nvik %A Manuchehr Abedi-Valugerdi %A Moustapha Hassan %J Clinical and Developmental Immunology %D 2010 %I Hindawi Publishing Corporation %R 10.1155/2010/142943 %X In the present paper, we have investigated early pathophysiological events in graft-versus-host disease (GVHD), a major complication to hematopoietic stem cell transplantation (HSCT). BLLB/c female mice conditioned with busulfan/cyclophosphamide (Bu-Cy) were transplanted with allogeneic male C57BL/6. Control group consisted of syngeneic transplanted Balb/c mice. In allogeneic settings, significant expansion and maturation of donor dendritic cells (DCs) were observed at day %U http://www.hindawi.com/journals/cdi/2010/142943/