%0 Journal Article
%T Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning
%A Behnam Sadeghi
%A Suleiman Al-Hashmi
%A Zuzana Hassan
%A Bjorn Rozell
%A Hernan Concha
%A Carin Lundmark
%A Kjell-Olov Gr nvik
%A Manuchehr Abedi-Valugerdi
%A Moustapha Hassan
%J Clinical and Developmental Immunology
%D 2010
%I Hindawi Publishing Corporation
%R 10.1155/2010/142943
%X In the present paper, we have investigated early pathophysiological events in graft-versus-host disease (GVHD), a major complication to hematopoietic stem cell transplantation (HSCT). BLLB/c female mice conditioned with busulfan/cyclophosphamide (Bu-Cy) were transplanted with allogeneic male C57BL/6. Control group consisted of syngeneic transplanted Balb/c mice. In allogeneic settings, significant expansion and maturation of donor dendritic cells (DCs) were observed at day
%U http://www.hindawi.com/journals/cdi/2010/142943/