%0 Journal Article
%T Necrosis cut¨¢nea por warfarina Warfarin-Induced skin necrosis
%A Edison Mu£¿oz
%A ¨®scar Jairo Valencia
%A Luis Guillermo Toro
%A Luis ALfonso Correa
%J Acta Medica Colombiana
%D 2012
%I Asociacion Colombiana de Medicina Interna
%X La necrosis cut¨¢nea por warfarina aparece entre 0.01-0.1% de los pacientes, afecta m¨¢s a mujeres con obesidad y antecedentes de enfermedad tromboemb¨®lica luego del quinto d¨ªa de su inicio. Se debe a un imbalance transitorio de los sistemas anticoagulante y procoagulante, caracterizado por flictenas hemorr¨¢gicas en zonas con tejido graso. Reportamos el caso de una necrosis cut¨¢nea por warfarina con un desenlace fatal. (Acta Med Colomb 2012; 37: 138-141). Warfarin-induced skin necrosis appears between 0.01% to 0.1% of patients. It affects mostly women with obesity and a history of thromboembolic disease after the fifth day of its administration, and is caused by a transient imbalance of procoagulant and anticoagulant systems, characterized by hemorrhagic blisters in areas with fatty tissue. (Acta Med Colomb 2012; 37: 138-141). We report the case of a warfarin-induced skin necrosis with fatal outcome.
%K necrosis
%K piel
%K warfarina
%K anticoagulantes
%K efectos adversos
%K necrosis
%K skin
%K warfarin
%K anticoagulants
%K adverse effects
%U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-24482012000300006