%0 Journal Article
%T DIVERSE REACTIONS OF )/¦Â-MERCAPTOALKANOIC ACIDS: IN THE SYNTHESES OF CONDENSED FUSED POLYCYCLIC HETEROCYCLES DIVERSE REAKTIONEN VON) / ¦Â-Mercaptoalkans ure ACIDS: In den Synthesen von CONDENSED polycyclischen HETEROCYCLEN
%A Batchu Chandrasekhar
%J Heterocyclic Letters
%D 2013
%I Raman Publications
%X This review describes the reactions of ¦Â-mercaptoalkanoic acids as building blocks for the synthesis of polyfunctional heterocycles with pharmacological interest. Annelated heterocycles have been prepared by the cyclocondensation reaction of ¦Â-mercaptoalkanoic acids with carbonyl function. This reaction takes place by nucleophilic addition, followed by cyclisation with elimination of water. The main objective of this survey is to provide a comprehensive account of the reactions of ¦Â-mercaptoalkanoic acids with carbonyl function, halovinylaldehydes, haloesters, heteroaromatic halides, halonitriles, imines in building various heterocycles and examining their potential in developing better chemotherapeutic agents
%K 2-mercaptoacetic acid
%K ¦Â-mercaptopropanoic acid
%K cyclocondensation
%K spiro heterocycles.
%U http://heteroletters.org/issue32/review3.html