%0 Journal Article %T Analgesia extradural posoperatoria en pacientes con lumbotom¨ªas %A Jorge Enrique Trujillo Salgado %A L¨¢zaro Pablo Vigoa S¨¢nchez %A Yolanda Sotolongo Molina %A Mar¨ªa Isabel Guti¨¦rrez %J Revista Cubana de Cirug¨ªa %D 1997 %I Editorial Ciencias M¨¦dicas %X Se estudiaron los efectos analg¨¦sicos de los siguientes f¨¢rmacos por v¨ªa extradural: epinefrina 0,1 mg, clonidina 0,15 mg, fentanyl 0,15 mg, morfina 2 mg y morfina 2 mg m¨¢s clonidina 0,15 mg, todos a adidos a la bupivaca¨ªna 0,5, 20 mL (100). Un total de 145 pacientes fueron estudiados en forma prospectiva. El an¨¢lisis estad¨ªstico se practic¨® mediante an¨¢lisis de varianza y se compararon los tiempos de analgesia m¨¢xima y las reacciones indeseables. La clonidina super¨® al fentanyl en este objetivo, pero su inclusi¨®n a la mezcla bupivaca¨ªna/morfina s¨®lo increment¨® la incidencia de efectos indeseables. En este estudio result¨® mejor la asociaci¨®n de bupivaca¨ªna 0,5 % y morfina 2 mg The analgesic effects of the following drugs by extradural route were studied: epinephrine 0.1 mg, clonidine 0.15 mg, fentanyl 0.15 mg, morphine 2 mg, and morphine 2 mg plus clonidine 0.15 mg, all of them added to bupivacaine 0.5 20 mL (100). A total number of 145 patients were studied in a prospective way. The statistical analysis was applied by the analysis of variance and the times of maximal analgesia and undesirable reactions were compared. Clonidine was to be better than fentanyl for this objective, but its inclusion to the mixture of bupivacaine/morphine only increased the incidence of adverse effects. It is concluded that the best combination was bupivacaine 0.5 % and morphine 2 mg %K ANALGESIA EPIDURAL %K DOLOR POSTOPERATORIO %K EPINEFRINA %K CLONIDINA %K FENTANIL %K MORFINA %K BUPIVACAINA %K ANALGESIA %K EPIDURAL %K PAIN %K POSTOPERATIVE %K EPINEPHRINE %K CLONIDINE %K FENTANYL %K MORPHINE %K BUPIVACAINE %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-74931997000200009