%0 Journal Article %T Construction of a traditional Chinese medicine syndrome-specific outcome measure: the Kidney Deficiency Syndrome questionnaire (KDSQ) %A Run Qiu Chen %A Chit Ming Wong %A Tai Hing Lam %J BMC Complementary and Alternative Medicine %D 2012 %I BioMed Central %R 10.1186/1472-6882-12-73 %X KDS-Yin and KDS-Yang were traditionally defined by expert opinion were validated by exploratory factor analysis (EFA) and structural equation modeling (SEM). Content validity was tested by EFA on a sample of 236 women from a seminar and SEM on another sample of 321 women from a postal survey. Other psychometric properties were tested on 292 women from the seminar at baseline and two systematically selected sub-samples: 54 who reported no changes in discomforts 11¨C12£¿days after the baseline and 31 who reported changes in discomforts 67¨C74£¿days after the baseline. All participants completed the KDSQ, the Greene Climacteric Scale and the standard 12-item Short Form Health Survey.The EFA and SEM established the measurement models of KDS-Yin and KDS-Yang supporting content validity of the KDSQ. Internal consistency was good (Cronbach¡¯s Alpha >0.70). Construct validity was supported by theoretically-derived levels of correlation with the established external measures. Test¨Cretest reliability was strong (ICCagreement: KDS-Yin, 0.94; KDS-Yang, 0.93). The KDSQ was responsive to changes over time as tested by effect size and longitudinal validity.The KDSQ was a valid and reliable measure for KDS-Yin and KDS-Yang in Hong Kong Chinese middle-aged women with menopausal symptoms. %U http://www.biomedcentral.com/1472-6882/12/73/abstract