%0 Journal Article %T Management of severe acute hepatitis B %A Khanna Sudeep %A Tandon Rakesh %J Hepatitis B Annual %D 2007 %I %X HBV infection is a major public health problem. Acute viral hepatitis B is successfully cleared in more than 95% of immunocompetent patients. HBV infection can cause severe acute hepatitis which can progress to acute liver failure. The purpose of this review is to discuss the immune response in acute hepatitis B and the possible role of HBV genotypes in development of severe acute HBV related hepatitis, define severe acute hepatitis B and to look at the role of the available antivirals in this clinical setting. %K Acute liver disease %K hepatitis B %K pregnancy %K severe acute hepatitis B %U http://www.hepatitisbannual.org/article.asp?issn=0972-9747;year=2007;volume=4;issue=1;spage=107;epage=117;aulast=Khanna