%0 Journal Article
%T A case of cutaneous large B-cell lymphoma of the legs appearing as chronic venous ulceration
%A Marta Carlesimo
%A Diego Orsini
%A Alessanrdra Narcisi
%A Claudia Abruzzese
%J Hematology Reports
%D 2012
%I PAGEPress Publications
%R 10.4081/hr.2012.e6
%X We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20+ and CD79a+, spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested.
%K Primary cutaneous B cell lymphoma
%K B cell lymphoma of the leg
%K Immunophenotype
%K Therapy
%U http://www.pagepress.org/journals/index.php/hr/article/view/3180