%0 Journal Article %T Comparison of a second with a first generation digital subtraction radiography system in the detection of subtle alveolar bone changes: An in vitro study %A Panagiotis TZOUTZOUKOS %A Kety NICOPOULOU-KARAYIANNI %A Aikaterini DONTA-BAKOGIANNI %J Hellenic Archives of Oral and Maxillofacial Surgery %D 2011 %I Hellenic Association for Oral and Maxillofacial Surgery %X Objectives: (1) To compare the diagnostic validity of a 2nd and a 1st generation DSR system in the detection of periodontal bone changes (2) to compare the shape and size of corresponding alveolar bone changes in the subtraction images from the two DSR systems. Methods: Periodontal lesions of varying sizes were created on a human dry skull. Standardized and non-standardized radiographs were acquired and subtracted with a 1st and a 2nd generation DSR system. Six oral radiologists evaluated the subtraction images. Results: The differences in all values of diagnostic accuracy between the two generations DSR systems were found to be statistically significant. No difference in the sensitivity of the two DSR systems was found when the largest lesions (1.6 mm) were studied. Median values for differences in shape and size were 1 and |1.5| re -spectively. The correlation coefficient (r) between the differences in the two parameters was 0.84. Conclusions: The 2nd generation DSR system has shown to have a satisfactory diagnostic accuracy only when bone changes of at least 1.6 mm in diameter are studied. %K digital subtraction radiography %K imageregistration %K periodontal bone changes %U http://www.haoms.org/haomsjournal/2011teuxos_3_article_3.pdf