%0 Journal Article %T Citrullus colocynthis as a bioavailable source of ¦Â-sitosterol, antihyperlipidemic effect of oil in rabbits %A Namama S. TALABANI %A Diary I. TOFIQ %J International Journal of Medicinal and Aromatic Plants %D 2012 %I %X A phytochemical study on the seed and kernel of Citrullus colocynthis has been carried out in the present paper. The results revealed the presence of the ¦Â-sitosterol in the kernel and seed in different percent (seed contain 16.92% and the kernel contain 6.62%). The lipid lowering active compound (¦Â-sitosterol) has been detected by using TLC, IR, UV and H1-NMR. The present study was designed to reveal the hypocholesterolemic effect of ¦Â-sitosterol on the serum total cholesterol and triglyceride in rabbits. Significant drop in serum total cholesterol and triglyceride was observed at 120 h after first administration. These results support the suggestion of Citrullus colocynthis oil as a treatment for hyperlipidemia. %K Citrullus colocynthis %K ¦Â-sitosterol %K Hyperlipidemea %U http://www.openaccessscience.com/pdf-files/vol2_3_sept2012/IJMAP_2_3_23_citrullus_colocynthis.pdf