%0 Journal Article
%T Detection of inducible clindamycin resistance among clinical isolates of staphylococci from a rural tertiary care hospital
%A Makam Sri Rangakumar Manjunath
%A Vijaya Rayapu
%A Dhandapany Senthil Pragash
%A Ivvala Anand Shaker
%A Sandeep Kasukurthy
%J International Journal of Medical Research and Health Sciences
%D 2013
%I Sumathi Publications
%R 10.5958/j.2319-5886.2.2.026
%X Clindamycin has been used successfully to treat pneumonia and soft tissue infections caused by methicillin-resistant Staphylococcus aureus. However, Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to Macrolide, Lincosamine and Streptogramin antibiotics. A total of 96 staphylococcal isolates from different clinical specimens were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 47.22% of methicillin-resistant Staphylococcus aureus isolates and in 21.67% of methicillin-sensitive Staphylococcus aureus isolates. In our setting, clindamycin is safe and effective agent to treat both systemic sand localized Staphylococcal infections, but we recommend that staphylococci isolates, particularly methicillin-resistant Staphylococcus aureus
%K Inducible clindamycin resistance
%K Methicillin resistant Staphylococcus aureus
%K D test.
%U http://ijmrhs.com/vi2/1.10%20Detection%20of%20inducible%20clindamycin%20resistance%20among%20clinical%20isolates%20of%20staphylococci%20from%20a%20rural%20tertiary%20care%20hospital.pdf