%0 Journal Article
%T Preliminary clinical study of left ventricular myocardial strain in patients with non-ischemic dilated cardiomyopathy by three-dimensional speckle tracking imaging
%A Fengxia Duan
%A Mingxing Xie
%A Xinfang Wang
%A Yuman Li
%A Lin He
%A Lan Jiang
%A Qian Fu
%J Cardiovascular Ultrasound
%D 2012
%I BioMed Central
%R 10.1186/1476-7120-10-8
%X Apical full-volume images were acquired from 65 patients with non-ischemic DCM (DCM group) and 59 age-matched normal controls (NC group), respectively. The following parameters were measured by 3D-STE: the peak systolic radial strain (RS), circumferential strain (CS), longitudinal strain (LS) of each segment. Then all the parameters were compared between the two groups.The peak systolic strain in different planes had certain regularities in normal groups, radial strain (RS) was the largest in the mid region, the smallest in the apical region, while circumferential strain (CS) and longitudinal strain (LS) increased from the basal to the apical region. In contrast, the regularity could not be applied to the DCM group. RS, CS, LS were significantly decreased in DCM group as compared with NC group (P < 0.001 for all). The interobserver, intraobserver and test-retest reliability were acceptable.3D-STE is a reliable tool for evaluation of left ventricular myocardial strain in patients with non-ischemic DCM, with huge advantage in clinical application.Non-ischemic dilated cardiomyopathy (DCM) is the most common cardiomyopathy worldwide, with significant mortality. In this disorder, dilation and impaired contraction of the left or both ventricles develops [1]. DCM is characterized by dilated ventricles and systolic dysfunction, and the clinical symptom of non-ischemic DCM is heart failure, which is often associated with arrhythmia and sudden death [2,3]. Correct evaluation of the patient's myocardial function has important clinical significance in the diagnosis, therapeutic effect assessment and prognosis in non-ischemic DCM patients.In recent years, the research on myocardial function in patients with non-ischemic DCM has become a hot topic in cardiovascular ultrasound [4-6], which mainly based on tissue Doppler imaging and two-dimensional speckle tracking imaging. However, the measurements of tissue Doppler imaging are angle dependent. Even though two-dimensional speckle
%K Echocardiography
%K Dilated cardiomyopathy
%K Ventricular function
%K left
%K Three dimensional speckle-tracking imaging
%U http://www.cardiovascularultrasound.com/content/10/1/8