%0 Journal Article
%T Ciliated hepatic foregut cyst in a patient with renal cell carcinoma
%A Todd Straus
%A Vladimir Osipov
%J BMC Cancer
%D 2006
%I BioMed Central
%R 10.1186/1471-2407-6-244
%X We present in this case report a ciliated hepatic foregut cyst found incidentally in the setting of renal carcinoma. The patient was a man known to have a large renal mass, assumed to be cancer, and a liver mass suspicious for metastatic disease. This liver mass was cystic and upon further analysis showed ciliated epithelial lining. We describe the gross and histological appearance, as well as a brief discussion of ciliated hepatic foregut cysts.We report the first case of a patient with coexisting renal cell carcinoma and a ciliated hepatic foregut cyst. While this may represent a coincidental finding, a possibility of a neoplastic or non-neoplastic disorder associated with ciliated hepatic foregut cysts can not be completely ruled out.Ciliated hepatic foregut cyst (CHFC) is a rare cystic lesion of the liver found in all age groups. It was first described in 1857 by Friedrich who hypothesized its congenital derivation and was later named CHFC in 1984 by Wheeler and Edmondson [1]. Since its first descriptions less than 80 cases have been reported in the English literature. Histologically, the cyst is lined by ciliated psuedostratified columnar epithelium with scattered goblet cells. The wall of the cyst is composed of subepithelial connective tissue, 1¨C3 smooth muscle layers, and a fibrous outer capsule. Usually the cysts are found incidentally at autopsy or on radiology scans for unrelated conditions [2]. There are only six reported cases of CHFC in patients with cancer. The lesion rarely causes any symptoms, and when it does, usually is from mass effect on liver structures such as the portal vein [3]. For many years this lesion was considered completely benign, however there have been two reported cases of squamous cell carcinoma occurring within these cysts [4,5]. As a result, current ideas on how to manage a diagnosis of CHFC are changing. We describe the first case where CHFC was seen in a patient with renal cell carcinoma.The patient is a 63-year-old man who i
%U http://www.biomedcentral.com/1471-2407/6/244