%0 Journal Article
%T In-hospital death in acute coronary syndrome was related to admission glucose in men but not in women
%A Julio Takada
%A Rog¨¦rio Ramos
%A Larissa Roza
%A Solange Avakian
%A Jos¨¦ Antonio Ramires
%A Antonio de Mansur
%J Cardiovascular Diabetology
%D 2012
%I BioMed Central
%R 10.1186/1475-2840-11-47
%X 959 ACS patients (363 women and 596 men) were grouped based on glycaemia£¿¡Ý£¿or£¿<£¿200 mg/dL and gender: men with glucose£¿<£¿200 mg/dL (menG-); women with glucose£¿<£¿200 mg/dL (womenG-); men with glucose£¿¡Ý£¿200 mg/dL (menG+); and women with glucose£¿¡Ý£¿200 mg/dL (womenG+). A logistic regression analysis compared the relation between gender and glycaemia groups and death, adjusted for coronary risk factors and laboratory data.menG- had lower mortality than menG£¿+£¿(OR£¿=£¿0.172, IC95% 0.062-0.478), and womenG£¿+£¿(OR£¿=£¿0.275, IC95% 0.090-0.841); womenG- mortality was lower than menG£¿+£¿(OR£¿=£¿0.230, IC95% 0.074-0.717). No difference was found between menG£¿+£¿vs womenG£¿+£¿(p£¿=£¿0.461), or womenG- vs womenG£¿+£¿(p£¿=£¿0.110). Age (OR£¿=£¿1.067, IC95% 1.031¨C1.104), EF (OR£¿=£¿0.942, IC95% 0.915-0.968), and serum creatinine (OR£¿=£¿1.329, IC95% 1.128-1.566) were other independent factors related to in-hospital death.Death was greater in hyperglycemic men compared to lower blood glucose men and women groups, but there was no differences between women groups in respect to glycaemia after adjustment for coronary risk factors.Acute coronary syndromes (ACS) are a set of presentations of coronary artery disease (CAD) and have in common unstable atherosclerotic coronary plaque. Unstable angina (UA), non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarction (STEMI) have differences in treatments and outcomes, but some markers of poor prognosis are common, such as clinical risk scores or several laboratory factors, including C-reactive protein, hyperglycaemia, and elevated brain natriuretic peptide type B [1,2].Admission blood glucose (ABG) is a risk factor of worse in-hospital and long-term prognosis in ACS [3,4], both in diabetic and nondiabetic patients [5], but its influence on mortality can be different along time after an acute event [6,7], and according to the diagnosis of patients admitted to intensive care units [8]. In ACS patients, women have more risk factors for CA
%K Mortality
%K Myocardial infarction
%K Hyperglycaemia
%K Sex
%K Glycaemia
%K In-hospital prognosis
%U http://www.cardiab.com/content/11/1/47