%0 Journal Article
%T Blood pressure and lipid management fall far short in persons with type 2 diabetes: results from the DIAB-CORE Consortium including six German population-based studies
%A Ina-Maria R¨¹ckert
%A Michaela Schunk
%A Rolf Holle
%A Sabine Schipf
%A Henry V£¿lzke
%A Alexander Kluttig
%A Karin-Halina Greiser
%A Klaus Berger
%A Grit M¨¹ller
%A Ute Ellert
%A Hannelore Neuhauser
%A Wolfgang Rathmann
%A Teresa Tamayo
%A Susanne Moebus
%A Silke Andrich
%A Christa Meisinger
%J Cardiovascular Diabetology
%D 2012
%I BioMed Central
%R 10.1186/1475-2840-11-50
%X The present analysis was based on the DIAB-CORE project, in which data from five regional population-based studies and one nationwide German study were pooled. All studies were conducted between 1997 and 2006. We assessed the frequencies of risk factors and co-morbidities, especially hypertension and dyslipidemia, in participants with and without T2D. The odds of no or insufficient treatment and the odds of pharmacotherapy were computed using multivariable logistic regression models. Types of medication regimens were described.The pooled data set comprised individual data of 15, 071 participants aged 45¨C74£¿years, including 1287 (8.5%) participants with T2D. Subjects with T2D were significantly more likely to have untreated or insufficiently treated hypertension, i.e. blood pressure of£¿>£¿= 140/90£¿mmHg (OR£¿=£¿1.43, 95% CI 1.26-1.61) and dyslipidemia i.e. a total cholesterol/HDL-cholesterol ratio£¿>£¿= 5 (OR£¿=£¿1.80, 95% CI 1.59-2.04) than participants without T2D. Untreated or insufficiently treated blood pressure was observed in 48.9% of participants without T2D and in 63.6% of participants with T2D. In this latter group, 28.0% did not receive anti-hypertensive medication and 72.0% were insufficiently treated. In non-T2D participants, 28.8% had untreated or insufficiently treated dyslipidemia. Of all participants with T2D 42.5% had currently elevated lipids, 80.3% of these were untreated and 19.7% were insufficiently treated.Blood pressure and lipid management fall short especially in persons with T2D across Germany. The importance of sufficient risk factor control besides blood glucose monitoring in diabetes care needs to be emphasized in order to prevent cardiovascular sequelae and premature death.Atherosclerosis accounts for most deaths in people with type 2 diabetes (T2D) and the age adjusted relative risk of coronary artery disease and peripheral arterial disease has been reported to be threefold higher than in the general population [1-3]. In a population-based stu
%K Type 2 Diabetes
%K Hypertension
%K Dyslipidemia
%K Adherence to guidelines
%K Pharmacological treatment
%U http://www.cardiab.com/content/11/1/50