%0 Journal Article
%T Association between gleason score, psa level, PSAD and prostate volume, in a series of patients with prostate adenocarcinoma
%A Benedetti-Padr車n In谷s
%A Barrios-Garc赤a L赤a
%A Segovia-Fuentes Javier
%J Revista Ciencias Biom谷dicas
%D 2012
%I Universidad de Cartagena
%X Introduction: Prostate cancer is the second most common cancer in men worldwide, itsincidence has increased by the use of early detection methods such as routine checks,the Prostate Specific Antigen (PSA) and its fractions as a method of screening andaccessibility and diagnostic efficacy of transrectal biopsy. The Gleason score is themethod most widely used and accepted histopathological to provide prognosticinformation for prostate cancer.Objective: To determine the association between the presence of prostateadenocarcinoma and the Gleason score with prostate volume, PSA level and PSA density(PSAD).Methodology: We reviewed the reports of studies of transrectal ultrasound of prostate,PSA and pathology reports of patients referred for consultation ultrasound for transrectalbiopsy of the prostate, for suspected adenocarcinoma, between august 2008 anddecember 2010, at a health services institution in the city of Cartagena. Colombia.Results: The presence of adenocarcinoma is associated with higher levels of PSA, aswell as with higher levels of DPSA. By contrast, isolated prostate volume did not showthis association. PSA levels between 4 and 10 ng/ml when the DPSA is less than 0.15ng/ml/cc, were associated with lower cancer risk. There was no correlation betweenthe level of PSA, prostate volume and PSAD with Gleason score of transrectal biopsies.Conclusion: The serum level of PSA is still useful in identifying aggressive prostatecancer, especially when you can exclude the elevation-related prostatic hyperplasiausing PSA density, and also that none of the pre-biopsy clinical trials analyzed had valueas predictor of tumor differentiation.RESUMEN:Introducci車n: el c芍ncer de pr車stata es el segundo c芍ncer en frecuencia en hombres anivel mundial, su incidencia ha aumentado por el uso de m谷todos de detecci車n precozcomo: las revisiones rutinarias, el Ant赤geno Prost芍tico Espec赤fico (PSA) y sus fracciones,como m谷todo de tamizaje y la accesibilidad y eficacia diagn車stica de la biopsia transrectal.La clasificaci車n de Gleason es el m谷todo histopatol車gico m芍s utilizado y aceptado paraproporcionar informaci車n sobre el pron車stico del c芍ncer de pr車stata.Objetivo: determinar la asociaci車n entre la presencia de adenocarcinoma prost芍tico yel puntaje de Gleason, con el volumen prost芍tico, el nivel de PSA y la densidad de PSA(DPSA).Metodolog赤a: se revisaron los informes de estudios de ecograf赤a transrectal depr車stata, PSA e informes de patolog赤a de pacientes remitidos a consulta ecogr芍fica pararealizaci車n de biopsia transrectal de pr車stata, por sospecha de adenocarcinoma, entreagos
%K Prostatic adenocarcinoma
%K Gleason score
%K Prostate specific antigen (PSA)
%K Prostate Specific Antigen Density (PSAD).
%U http://www.revistacienciasbiomedicas.com/index.php/revciencbiomed/article/view/174/139