%0 Journal Article
%T How does viral DNA find the nucleus of an infected cell?
%A Herbert Widulle
%J GMS Krankenhaushygiene Interdisziplin£¿r
%D 2012
%I 
%X If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism which transports a viral DNA-polymer from the cell wall to the nucleus and not to any other location. A possible mechanism is proposed which is in accordance with biophysical chemistry. The presented description of the mechanism uses non equilibrium thermodynamics to find a simple solution for the problem.
%K migration
%K virus genome
%K cell nucleus
%K mechanism
%K force
%K gradient
%K metabolism
%U http://www.egms.de/static/en/journals/dgkh/2012-7/dgkh000185.shtml