%0 Journal Article
%T Bladder metastases of appendiceal mucinous adenocarcinoma: a case presentation
%A Gianluigi Taverna
%A Matteo Corinti
%A Piergiuseppe Colombo
%A Fabio Grizzi
%A Mauro Severo
%A Alessando Piccinelli
%A Guido Giusti
%A Alessio Benetti
%A Paolo A Zucali
%A Pierpaolo Graziotti
%J BMC Cancer
%D 2010
%I BioMed Central
%R 10.1186/1471-2407-10-62
%X A case is reported of a 45-years old woman with mucinous cystadenocarcinoma of the appendix with bladder metastasis. Although ultrasonography and voided urinary cytology were negative, abdomen computed tomography (CT) scan and cystoscopy and subsequent pathological examination revealed a mass exclusively located in the anterior wall of the bladder. Histopathology of the transurethral bladder resection revealed a bladder adenocarcinoma [6 cm (at the maximum diameter) กม 2,5 cm; approximate weight: 10 gr] with focal mucinous aspects penetrating the muscle and perivisceral fat. Laparotomy evidenced the presence of a solid mass of the appendix (2,5 cm กม 3 cm กม 2 cm) extending to the loco-regional lymph nodes. Appendectomy and right hemicolectomy, linfoadenectomy and partial cystectomy were performed. The subsequent pathological examination revealed a mucinous cystadenocarcinoma of the appendix with metastatic cells colonising the anterior bladder wall and several colic lymph nodes.The rarity of the appendiceal carcinoma invading the urinary bladder and its usual involvement of nearest organs and the posterior bladder wall, led us to describe this case which demonstrates the ability of the appendiceal cancer to metastasize different regions of urinary bladder.The appendiceal adenocarcinoma invading the urinary bladder is extremely rare [1-4], and it is very difficult to be diagnosed before the surgical inspection. Here we describes a case of appendiceal cystoadenocarcinoma metastising the bladder anterior wall diagnosed in a patient with monosymptomatic episodes of gross hematuria. Our diagnostic schema and the adopted pharmacological treatment are also discussed.A 45-years old woman presented at our health centre (IRCCS Istituto Clinico Humanitas, Rozzano, Milan, Italy) with some episodes of gross hematuria. The ultrasonography and voided urinary cytology, and the physical examination were negative. The patient never had any gastrointestinal symptom and presented a negat
%U http://www.biomedcentral.com/1471-2407/10/62