%0 Journal Article
%T Imatinib-induced liver cirrhosis in a patient with advanced gastrointestinal stroma tumor (GIST)
%A Christoph Seidel
%A Martin Fenner
%A Florian L£¿nger
%A Heike Bantel
%A Arnold Ganser
%A Viktor Gr¨¹nwald
%J BMC Cancer
%D 2012
%I BioMed Central
%R 10.1186/1471-2407-12-186
%X We report a 49-year old male with a gastrointestinal stromal tumor (GIST) of the small bowel who developed liver cirrhosis under adjuvant imatinib treatment.Our report supports the notion that imatinib-induced hepatotoxicity may lead to acute liver damage with subsequent cirrhotic remodelling. Patients developing grade 3 or 4 hepatotoxicity during imatinib treatment should therefore be carefully evaluated for chronic liver disease.
%K GIST
%K Imatinib
%K Liver cirrhosis
%U http://www.biomedcentral.com/1471-2407/12/186/abstract