%0 Journal Article
%T Clarithromycin monohydrate: a synchrotron X-ray powder study
%A Shuji Noguchi
%A Sadahiro Fujiki
%A Yasunori Iwao
%A Keiko Miura
%J Acta Crystallographica Section E
%D 2012
%I International Union of Crystallography
%R 10.1107/s1600536812005090
%X In the crystal structure of the title compound, clarithromycin (CAM) monohydrate, C38H69NO13¡¤H2O, the water molecule behaves as a proton donor and is hydrogen bonded to the hydroxy O atom of the CAM cladinose ring. The hydroxy O atom also behaves as a proton donor, forming an intermolecular hydrogen bond with one of the hydroxy groups of the 14-membered aglycone ring. The CAM molecules are linked through these hydrogen bonds into chains running parallel to the c axis.
%U http://scripts.iucr.org/cgi-bin/paper?S1600536812005090