%0 Journal Article
%T Uncommon mandibular osteomyelitis in a cat caused by Nocardia africana
%A Marconi de Farias
%A Juliana Werner
%A M¨¢rcio Ribeiro
%A Sabrina Rodigheri
%A Carolina Cavalcante
%A Kung Chi
%A Larissa Anuska Condas
%A Tohru Gonoi
%A Tetsuhiro Matsuzama
%A Katsukiyo Yazama
%J BMC Veterinary Research
%D 2012
%I BioMed Central
%R 10.1186/1746-6148-8-239
%X A one-year-old non-neutered female cat, raised in a rural area, was admitted to the Companion Animal Hospital-PUCPR, S£¿o Jos¨¦ dos Pinhais, State of Paran¨¢, Brazil, with a history a progressive facial lesion, difficulty apprehending food, loss of appetite, apathy and emaciation. Clinical examination showed fever, submandibular lymphadenitis, and a painless, 8 cm diameter mass, which was irregularly-shaped, of firm consistency, and located in the region of the left mandible. The skin around the lesion was friable, with diffuse inflammation (cellulitis), multiple draining sinuses, and exudation of serosanguinous material containing whitish ¡°sulfur¡± granules.Diagnosis was based initially in clinical signs, microbiological culture, cytological, and histopathological findings, and radiographic images. Molecular sequencing of 16S rRNA of isolate allowed diagnosis of Nocardia africana. Despite supportive care and antimicrobial therapy based on in vitro susceptibility testing the animal died.The present report describes a rare clinical case of feline osteomyelitis caused by Nocardia africana, diagnosed based upon a combination of clinical signs, microbiological culture, cytological and histopathological findings, radiographic images, and molecular methods. The use of modern molecular techniques constitutes a quick and reliable method for Nocardia species identification, and may contribute to identification to new species of Nocardia that are virulent in cats.Nocardiosis is an opportunistic disease for humans and domestic animals, caused by aerobic actinomycetes from the genus Nocardia. These organisms are ubiquitous, soil saprophytes, and are found in organic material, water and plants.In companion animals, nocardial infection is considered rare, and are characterized by suppurative to pyogranulomatous lesions, localized or disseminated [1].Routine diagnosis in companion animals is based on microbiological culture, and phenotypic characterization [2]. Currently, species of t
%K Cat
%K Nocardia africana
%K Feline nocardiosis
%K Osteomyelitis
%U http://www.biomedcentral.com/1746-6148/8/239