%0 Journal Article %T Risk factors for bovine Tuberculosis at the national level in Great Britain %A Paul R Bessell %A Richard Orton %A Piran C L White %A Mike R Hutchings %A Rowland R Kao %J BMC Veterinary Research %D 2012 %I BioMed Central %R 10.1186/1746-6148-8-51 %X Large herds and fattening herds are more likely to breakdown in all areas. In areas with lower perceived risk (longer testing intervals), the risk of breaking down is largely determined by the number of animals that a herd buys in from high incidence areas. In contrast, in higher perceived risk areas (shorter testing intervals), the risk of breakdown is defined by the history of disease and the probability of badger occurrence. Despite differences in the management of bTB across different countries of GB (England, Wales and Scotland), we found no significant differences in bTB risk at the national level after these other factors had been taken into account.This paper demonstrates that different types of farm are at risk of breakdown and that the most important risk factors vary according to bTB incidence in an area. The results suggest that significant gains in bTB control could be made by targeting herds in low incidence areas that import the greatest number of cattle from high incidence areas.The control of an infectious disease is often complicated when more than one host species are involved and one of those is a wildlife reservoir. This problem is exacerbated if the reservoir host is poorly understood or if the disease is difficult to manage in the reservoir population [1,2]. One of the best described examples of this is that of bovine Tuberculosis (bTB) in Great Britain (GB), caused by Mycobacterium bovis. Largely eliminated in many industrialised countries, in GB the disease was eliminated from most cattle herds during the 1960s [3]. However, since then prevalence has been gradually rising and the area affected growing in size [4]. It was soon suspected that this rise was related to the presence of the Eurasian badger (Meles meles), once it was recognised that badgers were a host for M. bovis[5,6]. However, the nature of the relationship to cattle bTB remained controversial and so the randomised badger culling trial (RBCT) was set up to investigate the effect %U http://www.biomedcentral.com/1746-6148/8/51