%0 Journal Article
%T Piperidine Promoted Regioselective Synthesis of ¦Á, ¦Â-unsaturated Aldehydes
%A A. H. Banday
%J Pakistan Journal of Chemistry
%D 2013
%I Chem Publisher
%X An efficient, facile and regioselective synthesis of ¦Á,¦Â-unsaturated aldehydes from ¦Â-hydroxynitriles is reported. The reaction iscarried out using DIBAL-H and promoted by piperidine under dry conditions at a temperature of -78 oC and can be described as aconcomitant reduction-elimination reaction. The same reaction if carried out in the absence of piperidine gives mainly theuneliminated reduction product. The products formed are of immense importance as synthons in a large number of chemicalreactions and biological processes.
%K ¦Á
%K ¦Â-unsaturated aldehydes
%K metal hydrides
%K DIBAL-H
%K ¦Â-hydroxynitriles
%U https://www.pjchm.com/images/pdf/3_1_Paper_3.pdf