%0 Journal Article
%T 2-(2-{[4-Oxo-3-(2-phenylethyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}ethyl)-2,3-dihydro-1H-isoindole-1,3-dione
%A Adel S. El-Azab
%A Alaa A.-M. Abdel-Aziz
%A Abdulrahman M. Al-Obaid
%A Seik Weng Ng
%J Acta Crystallographica Section E
%D 2012
%I International Union of Crystallography
%R 10.1107/s1600536812025883
%X In the title compound, C26H21N3O3S, the quinazolinyl group is essentially planar [r.m.s. deviation for the 10 non-H atoms = 0.057  ]. The isoindoline-1,3-dione group is linked by an SCH2CH2 chain to the pyrimidinyl C atom that lies between the two N atoms. Also, the phenyl group is linked by a CH2CH2 chain at the N atom adjacent to the carbonyl group. This results in a conformation with these substituents lying to either side of the central quinazolinyl unit, with the former being approximately parallel [dihedral angle = 4.93 (7)¡ã], and the phenyl group being inclined [dihedral angle = 71.61 (9)¡ã] to the central quinazolinyl fused-ring system. In the crystal, molecules are consolidated into a three-dimensional architecture by C¡ªH...O interactions, involving all three carbonyl-O atoms, and ¦Ð¨C¦Ð interactions occurring between the pyrimidinyl and isoindole-benzene rings [inter-centroid distance = 3.5330 (13)  ].
%U http://scripts.iucr.org/cgi-bin/paper?S1600536812025883