%0 Journal Article %T Volume of blood suctioned during vacuum-assisted breast biopsy predicts later hematoma formation %A Flora Zagouri %A Theodoros N Sergentanis %A Philip Domeyer %A Dimosthenis Chrysikos %A Georgia Giannakopoulou %A Nikolaos V Michalopoulos %A Panagiotis Safioleas %A Ioannis Flessas %A Effrosyni Panopoulou %A Garifallia Bletsa %A George C Zografos %J BMC Research Notes %D 2010 %I BioMed Central %R 10.1186/1756-0500-3-70 %X 177 women underwent VABB according to standardized protocol. The volume of blood suctioned and hematoma formation were noted at the end of the procedure, as did the subsequent development and progression of hematoma. First- and second-order logistic regression was performed, where appropriate. Cases with hematoma presented with greater volume of blood suctioned (63.8 ¡À 44.7 cc vs. 17.2 ¡À 32.9 cc; p < 0.001, Mann-Whitney-Wilcoxon test for independent samples, MWW); the likelihood of hematoma formation was increasing till a volume equal to 82.6 cc, at which the second-order approach predicts a maximum. The volume of blood suctioned was positively associated with the duration of the procedure (Spearman's rho = 0.417, p < 0.001); accordingly, hematoma formation was also positively associated with the latter (p = 0.004, MWW). The volume of blood suctioned was not associated with patients' age, menopausal status and histopathological diagnosis.The likelihood of hematoma is increasing along with increasing amount of blood suctioned, reaching a plateau approximately at 80 cc of blood lost.The use of stereotactic vacuum breast biopsy (VABB) is increasing in clinical practice for the assessment of non-palpable mammographic lesions [1-3]. Taking a larger volume of tissue than a standard core biopsy, VABB seems capable of "forgiving" minor targeting inaccuracies [1-3]. That said, it is not without complication, its main one being hematoma formation [1]. Given that VABB is performed in the outpatient setting and women are discharged within one hour after biopsy, the suspicion for hematoma formation, as well as its progression, seems crucial. Worthy to mention is that neither the volume of blood suctioned and collected in the device's bin nor its implications have ever been studied in detail.The objective of this study is to evaluate whether the volume of blood suctioned during VABB is associated with hematoma formation and progression, patient's age and histology of the lesion. %U http://www.biomedcentral.com/1756-0500/3/70