%0 Journal Article
%T Prostatic Injection of Botulinum A Toxin: An Alternative Treatment for Benign Prostatic Hyperplasia
%A Aliasghar Yarmohamadi
%A Samira Yaghobi
%A Mahmoud Molaee
%J Knowledge & Health Journal
%D 2009
%I Shahroud University of Medical Sciences
%X Introduction: We examined the clinical effectiveness of prostate injection of botulinum A toxin in the treatment of BPH. Methods: In this deh1ive study 55 men with BPH who had failed medical treatment and were poor risks for surgery were treated by injection of botulinum A toxin into different parts of the transition zone. Amounts of prostate-specific antigen(PSA) prostate symptom scores quality-of-life index prostate volume postvoid residual urine volume and peak urinary flow rates were recorded and compared for all patients before injection and 3 and 6 months after the injection. Results: The mean patient age was 78¡À2.5 years. The mean symptom score and quality-of-life index significantly improved after 3 months. Maximal urinary flow rate (Qmax) showed a significant increase after 3 and 6 months of treatment. Postvoid residual urine volume had a significant decrease after 3 and 6 months (P0.05). Prostate volume decreased from 65¡À8 ml to 59¡À6 ml within 1 month and to 49¡À5 ml within 3 months (P
%K Prostate
%K Botulinum A toxin
%K Benign prostatic hyperplasia (BPH).
%U http://mag.shmu.ac.ir/library/upload/article/af_22453244-1-2.pdf