%0 Journal Article
%T Determination of Pioglitazone Hydrochloride in Tablets by High-Performance Liquid Chromatography
%A AMR Lotfy Saber
%J Pakistan Journal of Analytical and Environmental Chemistry
%D 2008
%I University of Sindh
%X A rapid and accurate HPLC method has been developed for the determination of pioglitazone hydrochloride in tablets. Chromatographic analysis was performed on a Nova-Pak  C18 column (3.9mm x 150mm, 5¦Ìm) with a mixture of ammonium formate buffer adjusted with formic acid to pH 3 and acetonitrile (75:25, v/v) as mobile phase, at flow rate of 1.0 mL min-1, and UV detection at 225 nm. The determination was completed in less than 12 min. Linearity ¡Ý 0.5 ¦ÌgmL-1, accuracy ¡Ý 99.14 %, and precision ¡Ü 0.6 % were found to be acceptable over the range 0.5 - 20 ¦ÌgmL-1.
%K Pioglitazone
%K Tablets
%K HPLC.
%U http://www.ceacsu.edu.pk/PDF%20file/Journal%20Volume%209,%20Issue%202/10.pdf