%0 Journal Article
%T Meningiomas: Hallazgos cl赤nicos y morfol車gicos en una casu赤stica de 24 a os
%A Alipio Hern芍ndez
%A Ghislaine C谷spedes
%A Carmen Lara
%A Jes迆s Gonz芍lez
%J Gaceta M谷dica de Caracas
%D 2008
%I Scientific Electronic Library Online
%X Los meningiomas son neoplasias primarias frecuentes del sistema nervioso central, usualmente benignas y susceptibles de curaci車n mediante cirug赤a. Se presentan los hallazgos cl赤nicos y morfol車gicos en una casu赤stica de 580 meningiomas diagnosticados durante el per赤odo 1980 a 2003. Estos tumores representaron el 16 % de las neoplasias del sistema nervioso central y la gran mayor赤a fueron 迆nicos (85 % de los casos), con localizaci車n intracraneana preferente y manifestaciones cl赤nicas relacionadas con el tama o y localizaci車n del tumor. Afectaron con mayor frecuencia a mujeres (relaci車n 2,4:1) y a pacientes con edades comprendidas entre los 30 a 59 a os (67 % de los casos). Seg迆n la clasificaci車n histol車gica de la Organizaci車n Mundial de la Salud, 80 % de los meningiomas correspondieron al grado histol車gico I (benignos), 17 % al grado II (at赤picos) y apenas 3 % al grado III (malignos). El subtipo histol車gico m芍s frecuente fue la variante transicional. Resulta importante para el pat車logo reconocer y clasificar adecuadamente a los meningiomas, puesto que de ello depende el tratamiento y pron車stico de este tipo frecuente de neoplasia. Meningiomas are frequent primary neoplasms of the central nervous system, usually benign and susceptible to healing through surgery. The clinical and morphological discoveries are presented in a study of 580 meningiomasdiagnosed during the period 1980-2003. These tumors represented a 16 % of the neoplasms of the central nervous system and most of them were unique (85 % of thecases), with preferential intracranial localization andclinical manifestations related to the size and localization of the tumor. Women were affected more frequently (the rate female/male of 2.4:1) and patients with ages among 30 and 59 years (67 % of the cases). According to the histologic classification of the World Health Organization, 80 % of the meningiomas corresponded to histological grade I (benign), 17 % to grade II (atypical) and only 3 % to grade III (malignant). The most frequent histological subtype was the transitional variant. It is important for the pathologist to recognize and classify adequately the meningiomas, since upon this depends the treatment and prognosis of this frequent kind of neoplasm.
%K Meningioma
%K Clasificaci車n histol車gica
%K Cl赤nica
%K Meningioma
%K Histologic classification
%K Clinic
%U http://wwww.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0367-47622008000200002