%0 Journal Article
%T Thermal, Spectral, Fluorescence, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes Derived from 4-[(5-Bromo-thiophen-2-ylmethylene)-amino]-3-mercapto-6-methyl-5-oxo-[1,2,4]triazine
%A Kiran Singh
%A Yogender Kumar
%A Parvesh Puri
%A Chetan Sharma
%A Kamal Rai Aneja
%J International Journal of Inorganic Chemistry
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/873232
%X A new series of cobalt, nickel, copper, and zinc complexes of bidentate Schiff base derived from the condensation of 5-bromothiophene-2-carboxaldehyde with 4-amino-3-mercapto-6-methyl-5-oxo-[1,2,4]triazine were synthesized. Physical (magnetic measurements, molar conductance, TG), spectral (UV-Vis, IR, 1HNMR, fluorescence, ESR), and analytical data have established the structures of synthesized Schiff base and its metal complexes. The presence of coordinated water in metal complexes was confirmed by IR and TG studies. The Schiff base exhibits a strong fluorescence emission, contrast to this partial fluorescence quenching phenomena is observed in its metal complexes. A square planar geometry for Cu(II) and octahedral geometry for Co(II), Ni(II) and Zn(II) complexes have been proposed. The Schiff base and its metal complexes have been screened for antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa) and antifungal activities (Aspergillus niger, A. flavus). 1. Introduction Triazine chemistry has attracted attention due to the utility of melamine derivatives as starting material for a variety of polymers [1], as scavenging resins in organic manipulations [2] and in medicinal chemistry [3]. They provide a wide range of applications in the field of optics [4], herbicides [5], and pharmaceuticals [6]. These are valuable bases for estrogen receptor modulators and are also used as bridging agents to synthesize herbicides and in the production of drugs or polymers [7, 8]. Many derivatives of 1,2,4-triazine form colored complexes with different metal ions and can be used as analytical reagent for their determination [9]. A range of polymer-supported triazines and their metal-bound analogues were screened for use in catalysis and organic synthesis [10, 11]. Goodman et al. reported that triazine-derived copper complexes have superoxide radical scavenging activity in pathological processes [12]. In our last publication, we have reported that Schiff base derived from 4-amino-3-mercapto-6-methyl-5-oxo triazine shows antibacterial and antifungal activity and enhanced antimicrobial activity is observed, when the Schiff base is combined to transition metal ions [13]. Encouraged by above-mentioned finding, we found it is to investigate the thermal, spectral, fluorescence, and antimicrobial studies of cobalt, nickel, copper, and zinc complexes derived from 4-[(5-bromo-thiophen-2-ylmethylene)-amino]-3-mercapto-6-methyl-5-oxo triazine. 2. Experimental 2.1. Materials All the chemicals used in the present study were of analytical
%U http://www.hindawi.com/journals/ijic/2012/873232/