%0 Journal Article
%T Qualidade e autenticidade de folhas de chap¨¦u-de-couro (Echinodorus grandiflorus) oriundas de fornecedores de S o Paulo Quality and authenticity of leaves of "chap¨¦u-de-couro" (Echinodorus grandiflorus) from suppliers in S o Paulo
%A E.G.E. Dias
%A V.C.T. Valenzuela
%A M.R. Alves
%A M.G.R. Duarte
%J Revista Brasileira de Plantas Medicinais
%D 2013
%I UNESP
%X Echinodorus grandiflorus e Echinodorus macrophyllus, conhecidas como chap¨¦u-de-couro, s o empregadas de forma indistinta como anti-inflamat¨®rio. O objetivo deste trabalho foi realizar an¨¢lises f¨ªsico-qu¨ªmicas de tr¨ºs amostras (A, B e C) de folhas de chap¨¦u-de-couro (E. grandiflorus) provenientes de fornecedores de S o Paulo buscando avaliar a qualidade e autenticidade destas amostras considerando a Farmacop¨¦ia Brasileira, 5a edi  o, como refer¨ºncia. Verificou-se que as amostras estavam de acordo com as especifica  es farmacopeicas em rela  o ¨¤s caracter¨ªsticas organol¨¦pticas, material estranho, umidade, cinzas totais, cinzas sulfatadas (exceto amostras A e B) e teores de derivados de ¨¢cido o-hidroxicinamico (exceto amostra A). Na descri  o macro e microsc¨®pica foram identificadas estruturas caracter¨ªsticas de E. grandiflorus. Ap¨®s an¨¢lise dos perfis cromatogr¨¢ficos por cromatografia em camada delgada de s¨ªlica (CCDS) constatou-se a presen a de ¨¢cido caf¨¦ico, isoorientina e swertiajaponina, conforme a monografia da esp¨¦cie. A amostra C foi a ¨²nica droga vegetal aprovada segundo os crit¨¦rios da Farmacopeia Brasileira, evidenciando-se a necessidade da realiza  o do controle de qualidade de mat¨¦rias-primas vegetais para garantir a obten  o de fitoter¨¢picos seguros e eficazes. Echinodorus grandiflorus and Echinodorus macrophyllus, known as "chap¨¦u-de-couro", have been differently used as anti-inflammatory agents. The aim of the present study was to carry out physicochemical analyses of three leaf samples (A, B and C) from "chap¨¦u-de-couro" (E. grandiflorus) obtained from suppliers in S o Paulo to assess the quality and the authenticity of these samples according to the Brazilian Pharmacopoeia (BP) 5th edition. All samples were in agreement with the specifications of the Pharmacopoeia considering their organoleptic characteristics, foreign material, humidity, total ash and sulfated ash (except for samples A and B), as well as the levels of o-hydroxycinnamic acid derivatives (except for sample A). Macroscopic and microscopic analysis of the samples revealed structures typical of E. grandiflorus. Analysis of chromatographic profiles by thin-layer chromatography (TLC) on silica gel indicated the presence caffeic acid, isoorientin and swertiajaponin, which are in accordance with the monography for this species. Sample C was the only plant drug approved according to the criteria of the Brazilian Pharmacopoeia, evidencing the need of quality control of raw plant material to ensure the production of safe and effective phytomedicines.
%K Echinodorus grandiflorus
%K autenticidade
%K perfil cromatogr¨¢fico
%K marcadores morfol¨®gicos
%K Echinodorus grandiflorus
%K authenticity
%K chromatographic profile
%K morphological markers
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-05722013000200013