%0 Journal Article
%T Facile synthesis of some novel 2-substituted-4,6-diarylpyrimidines using 4 ' -hydroxy-3 ' ,5 ' -dinitrochalcones and S-benzylthiouronium chloride
%A K. L. Ameta
%A Biresh Kumar
%A Nitu S. Rathore
%A B. L. Verma
%J Organic Communications
%D 2012
%I ACG Publications
%X Various 4'-hydroxy-3',5'-dinitro substituted chalcones 1 and S-benzylthiouronium chloride (SBT) 2 in the presence of DMF-organic bases (morpholine/ pyrrolidine/ piperidine) gave 4,6-diaryl-2-(4-morpholinyl / 1-pyrrolidinyl /1-piperidinyl)- pyrimidines 4, 5 and 6 in a facile one-pot conversion. In an another attempt reactants 1 and 2 yielded intermediate 2-benzylthiopyrimidines 3, in presence of DMF, which on treatment with heterocyclic secondary amines gave products 4, 5 and 6 in an alternate two-step process.
%K Chalcone
%K S-benzylthiouronium chloride
%K heterocyclic secondary amines.
%U http://www.acgpubs.org/OC/2012/Volume%205/Issue%201/1-OC-1110-216.pdf