%0 Journal Article
%T Leisure time physical activity in middle age predicts the metabolic syndrome in old age: results of a 28-year follow-up of men in the Oslo study
%A Ingar Holme
%A Serena Tonstad
%A Anne Sogaard
%A Per Larsen
%A Lise Haheim
%J BMC Public Health
%D 2007
%I BioMed Central
%R 10.1186/1471-2458-7-154
%X Men residing in Oslo and born in 1923¨C32 (n = 16 209) were screened for cardiovascular diseases and risk factors in 1972/3. Of the original cohort, those who also lived in same area in 2000 were invited to a repeat screening examination, attended by 6 410 men. The metabolic syndrome was defined according to a modification of the National Cholesterol Education Program criteria. Leisure time physical activity, smoking, educational attendance and the presence of diabetes were self-reported.Leisure time physical activity decreased between the first and second screening and tracked only moderately between the two time points (Spearman's ¦Ñ = 0.25). Leisure time physical activity adjusted for age and educational attendance was a significant predictor of both the metabolic syndrome and diabetes in 2000 (odds ratio for moderately vigorous versus sedentary/light activity was 0.65 [95% CI, 0.54¨C0.80] for the metabolic syndrome and 0.68 [0.52¨C0.91] for diabetes) (test for trend P < 0.05). However, when adjusted for more factors measured in 1972/3 including glucose, triglycerides, body mass index, treated hypertension and systolic blood pressure these associations were markedly attenuated. Smoking was associated with the metabolic syndrome but not with diabetes in 2000.Physical activity during leisure recorded in middle age prior to the current waves of obesity and diabetes had an independent predictive association with the presence of the metabolic syndrome but not significantly so with diabetes 28 years later in life, when the subjects were elderly.The prevalence of diabetes mellitus and its precursor, the metabolic syndrome has increased markedly in many countries [1], including Norway, and diabetes is becoming common worldwide [2,3]. Obesity and its duration are major risk factors for the development of type 2 diabetes. A general trend towards a more sedentary society with the advent of modern electronic equipment and computers, more time spent in sedentary activities as tel
%U http://www.biomedcentral.com/1471-2458/7/154