%0 Journal Article
%T Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies
%A Sohinee Bhattacharya
%A Doris M Campbell
%A William A Liston
%A Siladitya Bhattacharya
%J BMC Public Health
%D 2007
%I BioMed Central
%R 10.1186/1471-2458-7-168
%X This was a retrospective cohort study, based on all nulliparous women delivering singleton babies in Aberdeen between 1976 and 2005. Women were categorized into five groups 每 underweight (BMI < 20 Kg/m2), normal (BMI 20 每 24.9 Kg/m2) overweight (BMI 25 每 29.9 Kg/m2), obese (BMI 30 每 34.9 Kg/m2) and morbidly obese (BMI > 35 Kg/m2). Obstetric and perinatal outcomes were compared by univariate and multivariate analyses.In comparison with women of BMI 20 每 24.9, morbidly obese women faced the highest risk of pre-eclampsia {OR 7.2 (95% CI 4.7, 11.2)} and underweight women the lowest {OR 0.6 (95% CI 0.5, 0.7)}. Induced labour was highest in the morbidly obese {OR 1.8 (95% CI 1.3, 2.5)} and lowest in underweight women {OR 0.8 (95% CI 0.8, 0.9)}. Emergency Caesarean section rates were highest in the morbidly obese {OR 2.8 (95% CI 2.0, 3.9)}, and comparable in women with normal and low BMI. Obese women were more likely to have postpartum haemorrhage {OR 1.5 (95% CI 1.3, 1.7)} and preterm delivery (< 33 weeks) {OR 2.0 (95% CI 1.3, 2.9)}. Birthweights less than 2,500 g were more common in underweight women {OR 1.7 (95% OR 1.2, 2.0)}. The highest risk of birth weights > 4,000 g was in the morbidly obese {OR 2.1 (95% CI 1.3, 3.2)} and the lowest in underweight women {OR 0.5 (95% CI 0.4, 0.6)}.Increasing BMI is associated with increased incidence of pre-eclampsia, gestational hypertension, macrosomia, induction of labour and caesarean delivery; while underweight women had better pregnancy outcomes than women with normal BMI.The rising rate of obesity is a major public health concern in the West, where 28% of pregnant women are overweight and 11% are obese [1]. In the United States, the incidence of obesity in pregnancy varies from 18.5% to 38.3% according to the definition used [2-5]. In the UK, 56% of all women are over the recommended BMI, with 33% of them classified as overweight (BMI > 25) and 23% obese (BMI > 30). Although the exact incidence of obesity in pregnant women in
%U http://www.biomedcentral.com/1471-2458/7/168