%0 Journal Article %T Exploring health systems research and its influence on policy processes in low income countries %A Adnan A Hyder %A Gerald Bloom %A Melissa Leach %A Shamsuzzoha B Syed %A David H Peters %A Future Health Systems: Innovations for Equity %J BMC Public Health %D 2007 %I BioMed Central %R 10.1186/1471-2458-7-309 %X This paper provides a review of the research-policy interface in low-income countries and proposes a conceptual framework, followed by directions for empirical approaches. First, four developmental perspectives are considered: social institutional factors; virtual versus grassroots realities; science-society relationships; and construction of social arrangements. Building on these developmental perspectives three research-policy interface entry points are identified: 1. Recognizing policy as complex processes; 2. Engaging key stakeholders: decision-makers, providers, scientists, and communities; and 3. Enhancing accountability. A conceptual framework with three entry points to the research-policy interface ¨C policy processes; stakeholder interests, values, and power; and accountability ¨C within a context provided by four developmental perspectives is proposed. Potential empirical approaches to the research-policy interface are then reviewed. Finally, the value of such innovative empirical analysis is considered.The purpose of this paper is to provide the background, conceptual framework, and key research directions for empirical activities focused on the research-policy interface in low income settings. The interface can be strengthened through such analysis leading to potential improvements in population health in low-income settings. Health system development cognizant of the myriad factors at the research-policy interface can form the basis for innovative future health systems.The interface between policymaking and research in low-income countries is highly complex. Health systems research in such settings face a number of challenges including under-investment, lack of human capacity, lack of public demand, inadequate utilization, and poor dissemination of results [1-3]. Mismatch between need for health research and investment has been highlighted and attempts made to address the '10/90' gap including: research capacity strengthening; promotion of research invest %U http://www.biomedcentral.com/1471-2458/7/309