%0 Journal Article
%T Acylsulfonamide safety-catch linker: promise and limitations for solid¨Cphase oligosaccharide synthesis
%A Jian Yin
%A Steffen Eller
%A Mayeul Collot
%A Peter H. Seeberger
%J Beilstein Journal of Organic Chemistry
%D 2012
%I 
%R 10.3762/bjoc.8.232
%X Safety-catch linkers are useful for solid-phase oligosaccharide synthesis as they are orthogonal to many common protective groups. A new acylsulfonamide safety-catch linker was designed, synthesized and employed during glycosylations using an automated carbohydrate synthesizer. The analysis of the cleavage products revealed shortcomings for oligosaccharide synthesis.
%K glycosaminoglycans (GAGs)
%K glycosylation
%K resins
%K safety-catch linker
%K solid-phase synthesis
%U http://dx.doi.org/10.3762/bjoc.8.232