%0 Journal Article
%T Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors
%A Chao Che
%A Song Li
%A Bo Yang
%A Shengchang Xin
%J Beilstein Journal of Organic Chemistry
%D 2012
%I 
%R 10.3762/bjoc.8.94
%X Sant-75 is a newly identified potent inhibitor of the hedgehog pathway. We designed a diversity-oriented synthesis program, and synthesized a series of Sant-75 analogues, which lays the foundation for further investigation of the structure¨Cactivity relationship of this important class of hedgehog-pathway inhibitors.
%K chemical diversity
%K diversity-oriented
%K hedgehog pathway
%K inhibitor
%K Sant-75
%K synthesis
%U http://dx.doi.org/10.3762/bjoc.8.94