%0 Journal Article
%T Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
%A Chao Yang
%A Yutian Shao
%A Kang Li
%A Wujiong Xia
%J Beilstein Journal of Organic Chemistry
%D 2012
%I 
%R 10.3762/bjoc.8.217
%X A new selaginellin named selaginellin O (1), along with three other known selaginellins (2¨C4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4¡¯-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity.
%K antioxidant
%K cytotoxicity
%K Selaginella tamariscina
%K selaginellin
%U http://dx.doi.org/10.3762/bjoc.8.217