%0 Journal Article
%T Iridium-catalyzed intramolecular [4 + 2] cycloadditions of alkynyl halides
%A Andrew Tigchelaar
%A William Tam
%J Beilstein Journal of Organic Chemistry
%D 2012
%I 
%R 10.3762/bjoc.8.201
%X Iridium-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were investigated by using [IrCl(cod)]2 as catalyst, and dppe was found to be the most suitable phosphine ligand for the reaction. No oxidative insertion of the iridium into the carbon¨Chalide bond was observed, and the reactions proceeded to provide the halogenated cycloadducts in good yield (75¨C94%). These results are the first examples of cycloadditions of alkynyl halides using an iridium catalyst.
%K alkynyl halide
%K cycloaddition
%K diene-tethered alkyne
%K iridium
%K transition-metal catalyst
%U http://dx.doi.org/10.3762/bjoc.8.201