%0 Journal Article
%T Aldol elaboration of 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridin-4-ones, masked precursors to acylpyridones
%A Raymond C. F. Jones
%A Abdul K. Choudhury
%A James N. Iley
%A Mark E. Light
%J Beilstein Journal of Organic Chemistry
%D 2012
%I 
%R 10.3762/bjoc.8.33
%X A core 4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-one scaffold is elaborated at C-3(Me) by base-mediated aldol condensation to give new 3-alkenyl-4,5,6,7-tetrahydroisoxazolo[4,3-c]pyridine-4-ones, which are masked forms related to the acylpyridone natural products.
%K aldol reaction
%K fused-ring systems
%K heterocycles
%K isoxazole
%K metalation
%K pyridone
%U http://dx.doi.org/10.3762/bjoc.8.33