%0 Journal Article
%T PHYTOCHEMICAL AND MICROBIAL SCREENING OF PARKINSONIA ACULEATA L. LEAVES
%A ABDULLAHI SHAFIU KAMBA1 AND LAWAL GUSAU HASSAN2
%J International Journal of Drug Development & Research
%D 2010
%I Chauhan Publishers
%X Preliminarily phytochemical and antimicrobial investigation of the crude extract of the leaves of parkinsoniaaculeata leaves showed the presence tannin, alkoloids,glycoside,terpenoids flavonoid, terpenes, streriodsvolatile oil and saponin.The presence of these secondary metabolites indicates the pharmacological property ofthe plant leaves. The crude ethanolic extract, petroleum ether and chloroform extracts were also found toinhibit pseudomonas aeruginosa, streprococcus faecalis staphylococcus aureus, escherichia coli, and salmonellatyphimurium and klebsiella sp. The tin layer chromatography(TLC) revealed four spots, three spots and twospots for ethanol, petroleum ether and chloroform extract respectively using ethyl acetate: hexane solventmixture. The minimum inhibitory concentrations (MIC) of the crude extracts were determined for the variousorganisms which ranged between 35 and 50 mg/ml while the minimum bactericidal concentration ( MBC)ranged between 45 and 60 mg/ml. parkinsonia aculeata could be a potential source of antimicrobial agents.
%K parkinsonia aculeata
%K phytochemical Screening
%K antimicrobial activity
%K minimum bactericidal concentration
%K minimum inhibitory concentrations
%U http://ijddr.com/PDF1/1.pdf