%0 Journal Article %T Betamethasone Can Significantly Decrease Level of Striatal Glutamate in Animal Model of Parkinson¡¯s Disease %A Mehdi Shafiee Ardestani %A Hadi Fathi-Moghaddam %J Iranian Journal of Pharmaceutical Research %D 2008 %I School of Pharmacy, Shahid Beheshti University of Medical Sciences %X In the present study, the effect of steroidal anti-inflammatory drug betamethasone (0.12, 0.24 mg/kg, i.p. acutely) on striatal glutamate level in Parkinsonian rats was studied using the microdialysis technique. Our results showed significant differences (p<0.05) in the level of striatal glutamate between treated and non-treated damaged rats %K Microdialysis %K Betamethasone %K Glutamate %K Parkinson¡¯s disease %K Rat Model %U BetamethasoneCanSignificantlyDecreaseLevelofStriatalGlutamateinAnimalModelofParkinsona£¿£¿sDisease