%0 Journal Article
%T Hyperlipidemia in migraine: Is it more frequent in migraineurs?
%A Alia Saberi
%A Hamid Reza Hatamian
%A Ehsan Kazemnejad
%A Nasim Ghorbannejad
%J Iranian Journal of Neurology
%D 2011
%I Tehran University of Medical Sciences
%X Background: Some coincidental disorders with migrainehave been introduced that may have role in itspathogenesis or aggravation. In this study we determinedthe relative frequency of hyperlipidemia as a coincidentaldisorder in patients affected by migraine.Methods: A total of 102 migraine-affected patientsaccording to International Headache Society (HIS) criteriaand 103 control subjects adjusted for age participated inthis case-control study. Their serum level of triglyceride,total cholesterol, low density lipoprotein cholesterol (LDL-C)and high density lipoprotein cholesterol (HDL-C) weremeasured.Results: A total of 84 women and 18 men with mean age of34.9 ¡À 11.8 years and 79 women and 24 men with mean ageof 32.8 ¡À 5.7 years constituted case and control groups,respectively. The means of serum triglyceride, totalcholesterol, HDL-C and LDL-C levels in case and controlgroups were 177.0 ¡À 118.2 versus 108.7 ¡À 37.2 mg/dl(P = 0.0001), 186.2 ¡À 44.1 versus 152.9 ¡À 3.7 mg/dl(P = 0.0001), 49.9 ¡À 12.5 versus 46.1 ¡À 10.7 mg/dl (P = 0.023)and 104.8 ¡À 33.7 versus 84.1 ¡À 34.0 mg/dl (P = 0.0001),respectively. The prevalence of hypertriglyceridemia andhypercholesterolemia in case and control groups were41.2% versus 18.4 % (P = 0.0001), and 36.3% versus 9.7%(P = 0.0001). According to multivariate analysis, odds ratioswere 3.11 (95% CI: 1.4 -6.6) and 17.4 (95% CI: 2.12-138.3),respectively. Odds ratio for low HDL-C was 0.2 (95% CI:0.08-0.49).Conclusion: Hypertriglyceridemia andhypercholesterolemia were more frequent inmigraineurs. Conversely, low HDL-C was less frequentamong the patients compared with non-migraineurs.
%K Migraine
%K Triglyceride
%K Cholesterol
%K Low Density Lipoprotein
%K High Density Lipoprotein
%U http://ijnl.tums.ac.ir/index.php/ijnl/article/view/68