%0 Journal Article
%T ASSESSMENT OF THE DIAGNOSTIC VALUE OF MR ENTEROGRAPHY IN CROHN¡¯S DISEASE ACTIVITY
%A Ramazan Jafari
%J Iranian Journal of Radiology
%D 2012
%I Tehran University of Medical Sciences
%X Background/Objective: Crohn's disease beginsfrom an early age and in the course of many years it frequently flares. Regarding the multisegmental involvement of GI and also its numerous mural and extramural complications, MRI as a noninvasive,repeatable diagnostic imaging modality withoutusing harmful X ray may demonstrate different involvements of Crohn's disease throughout the abdomen and pelvis.Patients and Methods: Thirty-one patients who suffered from Crohn's disease and had been under colonoscopy and biopsy, after preparation of the small bowel, were studied at sequences of T2HASTE, TRUE FISP and post contrast VIBE using MRI. The existence of 10 signs including mural thickening, mural enhancement, stratification, comb sign, nodular thickening, stricture, fistula, mesentric lymph node, multisegmental involvement and mural edema was assessedResults: MR enterography with regard to the carriedout protocol of this study lead to the proper diagnosis of 19 cases out of 21 cases of Crohn's disease diagnosed by colonoscopy and biopsy.Generally, the sensitivity and specificity of MR enterography were assessed as 90.5% and 90%, respectively (PPV=95%, NPV=81.8%). The symptoms related to mural involvement of the small bowel including mural thickening more than 4 mm, wall enhancement,mural edema, stratification and multisegmental involvement were of high sensitivity and specificity; the increase in wall thickening and mural enhancement had the highest sensitivity and specificity.Conclusion: MR enterography has high sensitivity and specificity for diagnosing Crohn's disease activity and is an excellent imaging modality for assessment of the activity of this disease.
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%U http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/21115.pdf&manuscript_id=21115